发明申请
- 专利标题： PHARMACEUTICAL FORMULATIONS OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES WITH PROTEASE INHIBITORS
- 专利标题（中）： 替代酰基氨基哌啶衍生物与蛋白酶抑制剂的药物制剂
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申请号： US13473683申请日： 2012-05-17
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公开(公告)号： US20120238583A1公开(公告)日： 2012-09-20
- 发明人: Tao Wang , Zhongxing Zhang , Nicholas A. Meanwell , John F. Kadow , Zhiwei Yin , Qiufen May Xue , Alicia Regueiro-Ren , John D. Matiskella , Yasutsugu Ueda
- 申请人： Tao Wang , Zhongxing Zhang , Nicholas A. Meanwell , John F. Kadow , Zhiwei Yin , Qiufen May Xue , Alicia Regueiro-Ren , John D. Matiskella , Yasutsugu Ueda
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; A61P31/18
摘要：
This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.