发明申请
- 专利标题： METHODS OF PREPARATION OF CONJUGATES
- 专利标题（中）： 共混物的制备方法
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申请号： US13397205申请日： 2012-02-15
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公开(公告)号： US20120238731A1公开(公告)日： 2012-09-20
- 发明人: Nathan Fishkin , Michael Miller , Wei Li , Rajeeva Singh
- 申请人： Nathan Fishkin , Michael Miller , Wei Li , Rajeeva Singh
- 申请人地址： US MA Waltham
- 专利权人： ImmunoGen, Inc.
- 当前专利权人： ImmunoGen, Inc.
- 当前专利权人地址： US MA Waltham
- 主分类号： C07K16/46
- IPC分类号： C07K16/46
摘要：
The present invention is directed to methods of preparing a conjugate of a cell-binding agent and a drug (such as a cytotoxic compound). The methods comprise the use of an imine reactive compound to enable efficient conjugations of cytotoxic compounds with cell binding agents.
公开/授权文献
- US09353127B2 Methods of preparation of conjugates 公开/授权日：2016-05-31
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