发明申请
- 专利标题: FUSED HETEROCYCLIC COMPOUND HAVING AMINO GROUP
- 专利标题(中): 具有AMINO集团的熔融杂环化合物
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申请号: US13514907申请日: 2010-12-09
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公开(公告)号: US20120245155A1公开(公告)日: 2012-09-27
- 发明人: Syuhei Yoshida , Issei Kato , Kouki Fuchino , Yuuji Kooriyama , Yoshiyasu Baba , Norihiko Tanimoto
- 申请人: Syuhei Yoshida , Issei Kato , Kouki Fuchino , Yuuji Kooriyama , Yoshiyasu Baba , Norihiko Tanimoto
- 申请人地址: JP Osaka-shi, Osaka
- 专利权人: Shionogi & Co., Ltd.
- 当前专利权人: Shionogi & Co., Ltd.
- 当前专利权人地址: JP Osaka-shi, Osaka
- 优先权: JP2009-282193 20091211
- 国际申请: PCT/JP2010/072121 WO 20101209
- 主分类号: A61K31/542
- IPC分类号: A61K31/542 ; C07D417/12 ; C07D498/04 ; A61P25/28 ; C07D279/08 ; C07D265/18 ; A61K31/5365 ; C07D513/04 ; C07D413/12
摘要:
The present invention provides, for example, a compound mentioned below as a medicament for treating or preventing the diseases induced by production, secretion or deposition of amyloid-βproteins.A compound of the formula (I): wherein R1, R2a, R2b, R3, R4, R5a, R5b, R6a, R6b, X, Y, Z, ring A and the dashed lines are defined in the specification, its pharmaceutically acceptable salt or a solvate thereof.