发明申请
US20120251488A1 USE OF TRUNCATED CYSTEINE IL28 AND IL29 MUTANTS TO TREAT CANCERS AND AUTOIMMUNE DISORDERS
审中-公开
使用截短的CYSTEINE IL28和IL29突变体治疗癌症和自身免疫性疾病
- 专利标题： USE OF TRUNCATED CYSTEINE IL28 AND IL29 MUTANTS TO TREAT CANCERS AND AUTOIMMUNE DISORDERS
- 专利标题（中）： 使用截短的CYSTEINE IL28和IL29突变体治疗癌症和自身免疫性疾病
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申请号： US13440066申请日： 2012-04-05
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公开(公告)号： US20120251488A1公开(公告)日： 2012-10-04
- 发明人: Paul O. Sheppard
- 申请人： Paul O. Sheppard
- 专利权人： ZymoGenetics, Inc.
- 当前专利权人： ZymoGenetics, Inc.
- 主分类号： A61K38/20
- IPC分类号： A61K38/20 ; A61P25/00
摘要：
Methods for treating patients with cancer and autoimmune disorders using IL-28 and IL-29 molecules. The IL-28 and IL-29 molecules include polypeptides that have homology to the human IL-28 or IL-29 polypeptide sequence and proteins fused to a polypeptide with IL-28 and IL-29 functional activity. The molecules can be used as a monotherapy or in combination with other known cancer and/or autoimmune therapeutics.
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