发明申请
- 专利标题: INHIBITORS OF AKT ACTIVITY
- 专利标题(中): AKT活动的抑制剂
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申请号: US13515326申请日: 2010-12-09
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公开(公告)号: US20120252806A1公开(公告)日: 2012-10-04
- 发明人: Michael J. Kelly, III , Mark E. Layton
- 申请人: Michael J. Kelly, III , Mark E. Layton
- 国际申请: PCT/US10/59654 WO 20101209
- 主分类号: A61K31/4375
- IPC分类号: A61K31/4375 ; C07D241/36 ; A61K31/517 ; A61K31/5377 ; A61P35/00 ; A61K31/497 ; A61K31/506 ; C07D487/04 ; A61K31/519 ; C07D471/04 ; C07D413/06
摘要:
The instant invention provides for compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer.
公开/授权文献
- US1621003A Casting reel 公开/授权日:1927-03-15
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