发明申请
US20120252854A1 CRYSTALLINE FORMS OF THIAZOLIDINEDIONE COMPOUND AND ITS MANUFACTURING METHOD
失效
噻唑烷二酮化合物的结晶形式及其制备方法
- 专利标题： CRYSTALLINE FORMS OF THIAZOLIDINEDIONE COMPOUND AND ITS MANUFACTURING METHOD
- 专利标题（中）： 噻唑烷二酮化合物的结晶形式及其制备方法
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申请号： US13465202申请日： 2012-05-07
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公开(公告)号： US20120252854A1公开(公告)日： 2012-10-04
- 发明人: Hisaki Kajino , Yutaka Ikeuchi , Hiroshi Miyamoto , Eiji Numagami , Satoru Nihei
- 申请人： Hisaki Kajino , Yutaka Ikeuchi , Hiroshi Miyamoto , Eiji Numagami , Satoru Nihei
- 申请人地址： JP Tokyo
- 专利权人： DAIICHI-SANKYO COMPANY, LIMITED
- 当前专利权人： DAIICHI-SANKYO COMPANY, LIMITED
- 当前专利权人地址： JP Tokyo
- 主分类号： C07D417/12
- IPC分类号： C07D417/12 ; A61P35/02 ; A61P35/00 ; A61K31/427 ; A61P3/10
摘要：
A crystalline form of a hydrate of a dihydrochloride 5-(4-{[6-(4-amino-3,5-dimethylphenoxy)-1-methyl-1-H-benzimidazol-2-yl]methoxy}benzyl)-1,3-thiazolidine-2,4-dione represented by the following formula: wherein the crystalline form shows main peaks at interplanar spacings of 10.42, 5.85, 5.52, 3.84, 3.46 and 2.95 angstroms in X-ray powder diffraction obtained with Cu Kα line radiation (wavelength λ=1.54 angstroms).
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