发明申请
US20120253050A1 SYNTHESIS OF 8-AMINO BORON DIPYRROMETHENES HAVING BLUE FLUORESCENCE
有权
具有蓝色荧光的8-氨基硼烷二氯甲烷的合成
- 专利标题: SYNTHESIS OF 8-AMINO BORON DIPYRROMETHENES HAVING BLUE FLUORESCENCE
- 专利标题(中): 具有蓝色荧光的8-氨基硼烷二氯甲烷的合成
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申请号: US13512734申请日: 2010-12-10
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公开(公告)号: US20120253050A1公开(公告)日: 2012-10-04
- 发明人: Eduardo Peña Cabrera , César Fernando Azael , Juan Orlando Flores
- 申请人: Eduardo Peña Cabrera , César Fernando Azael , Juan Orlando Flores
- 申请人地址: MX Guanajuato
- 专利权人: UNIVERSIDAD DE GUANAJUATO
- 当前专利权人: UNIVERSIDAD DE GUANAJUATO
- 当前专利权人地址: MX Guanajuato
- 优先权: MXMX/A/2009/013486 20091210
- 国际申请: PCT/MX2010/000151 WO 20101210
- 主分类号: C07F5/02
- IPC分类号: C07F5/02
摘要:
A family of six 8-amino boron dipyrromethenes having Formulas 1, 2, 3, 4, 6, and 7 has been prepared. The presence of the amine group alters the emission properties of the boron dipyrromethene, such that these compounds are characterized by unexpected blue fluorescence, providing for potential use as lasers. The compound having formula 1 has very high quantum yield. The 8-amino boron dipyrromethenes are prepared in a straightforward, high yield synthesis by substituting an amine group for the thiomethyl group at the 8 position in 8-thiomethyl boron dipyrromethene. The compounds having Formulas 6 and 7 may be used to incorporate peptides and proteins, thus providing biomolecules marked with fluorescent fragments.
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