发明申请
US20120258041A1 COMPOSITIONS AND METHODS FOR TREATING DISEASES OF PROTEIN AGGREGATION INVOLVING IC3B DEPOSITION
审中-公开
用于治疗涉及IC3B沉积的蛋白质聚集的疾病的组合物和方法
- 专利标题： COMPOSITIONS AND METHODS FOR TREATING DISEASES OF PROTEIN AGGREGATION INVOLVING IC3B DEPOSITION
- 专利标题（中）： 用于治疗涉及IC3B沉积的蛋白质聚集的疾病的组合物和方法
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申请号： US13441818申请日： 2012-04-06
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公开(公告)号： US20120258041A1公开(公告)日： 2012-10-11
- 发明人: Guriqbal S. Basi , Robin Barbour
- 申请人： Guriqbal S. Basi , Robin Barbour
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/18 ; C12P21/02 ; A61P11/00 ; A61K51/10 ; A61P25/28 ; A61P27/02 ; A61P19/02 ; C07K16/46 ; A61K39/00
摘要：
The invention provides antibodies that preferentially bind to iC3b relative to C3b. These antibodies serve to reduce the toxicity of this fragment and find use in treatment and prophylaxis of a variety of diseases associated with deposits of the fragment.
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