发明申请
US20120263713A1 Combination therapy of an afucosylated CD20 antibody with fludarabine and/or mitoxantrone
审中-公开
非糖基化CD20抗体与氟达拉滨和/或米托蒽醌组合治疗
- 专利标题: Combination therapy of an afucosylated CD20 antibody with fludarabine and/or mitoxantrone
- 专利标题(中): 非糖基化CD20抗体与氟达拉滨和/或米托蒽醌组合治疗
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申请号: US13490351申请日: 2012-06-06
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公开(公告)号: US20120263713A1公开(公告)日: 2012-10-18
- 发明人: Martin Dreyling , Daniel Alexander Heinrich , Frank Herting , Christian Klein
- 申请人: Martin Dreyling , Daniel Alexander Heinrich , Frank Herting , Christian Klein
- 优先权: EPEP09010488.6 20090814; EPEP10162391.6 20100510
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; A61P35/00
摘要:
The present invention is directed to the combination therapy of an afucosylated anti-CD20 antibody with fludarabine and/or mitoxantrone for the treatment of cancer, especially to the combination therapy of CD20 expressing cancers with an afucosylated humanized B-Ly1 antibody with fludarabine and/or mitoxantrone.
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