发明申请
US20120264140A1 METHODS AND KITS TO DETECT AND MONITOR OVARIAN CANCER AND PREECLAMPSIA
有权
检测和监测卵巢癌和前列腺癌的方法和工具
- 专利标题： METHODS AND KITS TO DETECT AND MONITOR OVARIAN CANCER AND PREECLAMPSIA
- 专利标题（中）： 检测和监测卵巢癌和前列腺癌的方法和工具
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申请号： US13454276申请日： 2012-04-24
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公开(公告)号： US20120264140A1公开(公告)日： 2012-10-18
- 发明人: Manish S. Patankar , Joseph P. Connor , Jennifer A. Belisle
- 申请人： Manish S. Patankar , Joseph P. Connor , Jennifer A. Belisle
- 申请人地址： US WI Madison
- 专利权人： Wisconsin Alumni Research Foundation
- 当前专利权人： Wisconsin Alumni Research Foundation
- 当前专利权人地址： US WI Madison
- 主分类号： G01N33/574
- IPC分类号： G01N33/574 ; G01N33/566
摘要：
The present invention provides methods and kits related to a prognostic, and, in certain embodiments, diagnostic indicator for ovarian cancer which comprises measuring the level of MUC16 bound to immune cells. The level of MUC16 bound to immune cells can by itself be an indicator of disease regression or recurrence, or this indicator can be used in conjunction with assays for serum CA125 and other diagnostic markers. The invention further provides methods and kits related to the detection of ovarian cancer by measuring levels of Siglec-9 expression on immune cells. As well, related methodologies are provided for the detection of preeclampsia in pregnant human subjects.
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