发明申请
US20120269817A1 Monoclonal Antibodies Against Tissue Factor Pathway Inhibitor
审中-公开
针对组织因子途径抑制剂的单克隆抗体
- 专利标题： Monoclonal Antibodies Against Tissue Factor Pathway Inhibitor
- 专利标题（中）： 针对组织因子途径抑制剂的单克隆抗体
-
申请号： US13057728申请日： 2009-08-04
-
公开(公告)号： US20120269817A1公开(公告)日： 2012-10-25
- 发明人: Zhuozhi Wang , John E. Murphy , Junliang Pan , Haiyan Jiang , Bing Liu
- 申请人： Zhuozhi Wang , John E. Murphy , Junliang Pan , Haiyan Jiang , Bing Liu
- 申请人地址： US NY Tarrytown
- 专利权人： BAYER HEALTHCARE LLC
- 当前专利权人： BAYER HEALTHCARE LLC
- 当前专利权人地址： US NY Tarrytown
- 国际申请： PCT/US09/52702 WO 20090804
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C12P21/08 ; C12N15/13 ; C07K16/18 ; A61P7/04
摘要：
Isolated monoclonal antibodies that bind human tissue factor pathway inhibitor (TFPI) and the isolated nucleic acid molecules encoding them are provided. Pharmaceutical compositions comprising the anti-TFPI monoclonal antibodies and methods of treating deficiencies or defects in coagulation by administration of the antibodies are also provided. Methods of producing the antibodies are also provided.
信息查询
