发明申请
US20120276007A1 IMAGING AGENTS AND METHODS OF IMAGING NAALADASE OR PSMA
审中-公开
成像剂及其形成方法NAALADASE或PSMA
- 专利标题： IMAGING AGENTS AND METHODS OF IMAGING NAALADASE OR PSMA
- 专利标题（中）： 成像剂及其形成方法NAALADASE或PSMA
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申请号： US13537789申请日： 2012-06-29
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公开(公告)号： US20120276007A1公开(公告)日： 2012-11-01
- 发明人: Martin Gilbert Pomper , Jiazhong Zhang , John L. Musachio , Alan P. Kozikowski
- 申请人： Martin Gilbert Pomper , Jiazhong Zhang , John L. Musachio , Alan P. Kozikowski
- 申请人地址： US DC Washington US MD Baltimore
- 专利权人： Georgetown University,The Johns Hopkins University
- 当前专利权人： Georgetown University,The Johns Hopkins University
- 当前专利权人地址： US DC Washington US MD Baltimore
- 主分类号： A61K51/04
- IPC分类号： A61K51/04 ; C07C69/78 ; C07C323/57
摘要：
The present invention relates to compounds particularly asymmetric urea compounds which are labeled with one or more radioisotopes and which are suitable for imaging or therapeutic treatment of tissues, organs, or tumors which express NAALADase and/or PSMA. In another embodiment, the invention relates to methods of imaging tissues, organs, or tumors using radiolabeled compounds of the invention, particularly tissues, organs, or tumors which express NAALADase and/or PSMA to which the compounds of the invention have an affinity.
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