Methods of selecting an enhanced uplink (EU) transport format combination (E-TFC) are disclosed. A maximum number of bits of scheduled data for an upcoming transmission may be determined, wherein the highest value is lower or equal to: K e , ref · S   G L e , ref · A ed , ref 2 · 10 Δ   harq / 10 , where SG is a serving grant, Le,ref is the number of EU dedicated physical data channels (E-DPDCHs) used for a selected reference E-TFC, Ke,ref is the number of data bits of the reference E-TFC, Δharq is a hybrid automatic repeat request (HARM) offset for a specific data flow to be transmitted as signaled by higher layers, and Aed,ref is a ratio derived from a parameter ΔE-DPDCH signaled by higher layers for the selected reference E-TFC.