发明申请
US20120282325A1 LIPOSOME OF IRINOTECAN OR ITS HYDROCHLORIDE AND PREPARATION METHOD THEREOF
审中-公开
铁氰菊酯或其盐酸盐的制备方法及其制备方法
- 专利标题： LIPOSOME OF IRINOTECAN OR ITS HYDROCHLORIDE AND PREPARATION METHOD THEREOF
- 专利标题（中）： 铁氰菊酯或其盐酸盐的制备方法及其制备方法
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申请号： US13512048申请日： 2009-12-03
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公开(公告)号： US20120282325A1公开(公告)日： 2012-11-08
- 发明人: Xinyong Tong , Guofeng Lei , Chengxia Yu , Liang Chen
- 申请人： Xinyong Tong , Guofeng Lei , Chengxia Yu , Liang Chen
- 申请人地址： CN Shanghai CN Lianyungang, Jiangsu
- 专利权人： SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.,JIANGSU HENGRUI MEDICINE CO., LTD.
- 当前专利权人： SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.,JIANGSU HENGRUI MEDICINE CO., LTD.
- 当前专利权人地址： CN Shanghai CN Lianyungang, Jiangsu
- 国际申请： PCT/CN09/75298 WO 20091203
- 主分类号： A61K9/127
- IPC分类号： A61K9/127 ; A61P35/00 ; A61K31/4745
摘要：
A liposome of irinotecan or irinotecan hydrochloride and its preparation method are disclosed. The liposome contains irinotecan or irinotecan hydrochloride, neutral phospholipid and cholesterol, wherein the weight ratio of the cholesterol to the neutral phospholipid is 1:3 to 1:5. The liposome is prepared by an ion gradient method.
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