An actuator assembly for an adjustable fluid-filled lens is provided. In some embodiments, the actuator assembly includes a clamp configured to adjust the optical power of the fluid lens module when the clamp is compressed. In some embodiments, a magnetic element is configured to adjust the optical power of the fluid-filled lens. In some embodiments, a plunger changes the optical power of the fluid lens module. In some embodiments, a reservoir is configured such that deformation of the reservoir changes the optical power of the fluid-filled lens. In some embodiments, a balloon is configured to deform the reservoir. In some embodiments, an adjustable fluid-filled lens includes a septum configured to be pierceable by a needle and automatically and fluidly seal a fluid chamber after withdrawal of the needle. In some embodiments, a thermal element can heat fluid within a fluid chamber to change an optical power of the lens module.