发明申请
US20120288566A1 LIQUID PRECURSOR COMPOSITIONS AND USES THEREOF FOR A PH-DEPENDANT SUSTAINED RELEASE TREATMENT OF ORAL DISORDERS
审中-公开
液体前列腺素组合物及其用于依赖于依赖性持续释放口腔疾病的药物
- 专利标题： LIQUID PRECURSOR COMPOSITIONS AND USES THEREOF FOR A PH-DEPENDANT SUSTAINED RELEASE TREATMENT OF ORAL DISORDERS
- 专利标题（中）： 液体前列腺素组合物及其用于依赖于依赖性持续释放口腔疾病的药物
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申请号： US13500394申请日： 2010-10-05
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公开(公告)号： US20120288566A1公开(公告)日： 2012-11-15
- 发明人: Michael Friedman , Doron Steinberg , Irith Gati
- 申请人： Michael Friedman , Doron Steinberg , Irith Gati
- 申请人地址： IL Jerusalem
- 专利权人： Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
- 当前专利权人： Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
- 当前专利权人地址： IL Jerusalem
- 国际申请： PCT/IL10/00808 WO 20101005
- 主分类号： A61K47/32
- IPC分类号： A61K47/32 ; A61K47/46 ; A61K31/09 ; A61P31/00 ; A61K31/4174 ; A61K31/44 ; A61K9/00 ; A61K47/38 ; A61K31/155
摘要：
The present invention discloses liquid precursor compositions adapted for application on a hard surface in the oral cavity, comprising at least one therapeutic agent suitable for the treatment of oral disorders, at least one acidic-pH sensitive polymer, at least one hydrophobic polymer, and a pharmaceutically acceptable volatile carrier, wherein a weight ratio between said at least one hydrophobic polymer and said at least one acidic-pH sensitive polymer is larger than 1. The invention also discloses formulations formed of the solidification of these compositions, and methods for treating oral disorders by applying these compositions on hard surfaces in the oral cavity or to be placed in the oral cavity.