- 专利标题： SPIRO-OXINDOLE MDM2 ANTAGONISTS
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申请号： US13469928申请日： 2012-05-11
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公开(公告)号： US20120289494A1公开(公告)日： 2012-11-15
- 发明人: Shaomeng Wang , Wei Sun , Angelo Aguilar , Carlos Garcia-Echeverria
- 申请人： Shaomeng Wang , Wei Sun , Angelo Aguilar , Carlos Garcia-Echeverria
- 申请人地址： FR Paris US MI Ann Arbor
- 专利权人： Sanofi,The Regents of the University of Michigan
- 当前专利权人： Sanofi,The Regents of the University of Michigan
- 当前专利权人地址： FR Paris US MI Ann Arbor
- 主分类号： A61K31/407
- IPC分类号： A61K31/407 ; A61K31/5377 ; A61P35/00 ; A61K31/438 ; A61K31/41 ; C07D487/10 ; C07D471/20
摘要：
Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases.
公开/授权文献
- US08629141B2 Spiro-oxindole MDM2 antagonists 公开/授权日：2014-01-14
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