发明申请
- 专利标题： COMBINATION OF KINASE INHIBITORS AND USES THEREOF
- 专利标题（中）： 激酶抑制剂的组合及其用途
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申请号： US13403856申请日： 2012-02-23
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公开(公告)号： US20120294930A1公开(公告)日： 2012-11-22
- 发明人: Pingda Ren , Yi Liu , Katayoun Jessen , Xin Guo , Christian Rommel , Troy Edward Wilson
- 申请人： Pingda Ren , Yi Liu , Katayoun Jessen , Xin Guo , Christian Rommel , Troy Edward Wilson
- 申请人地址： US CA La Jolla
- 专利权人： Intellikine LLC
- 当前专利权人： Intellikine LLC
- 当前专利权人地址： US CA La Jolla
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; A61K31/436 ; A61K31/4745 ; A61K31/517 ; A61K31/5025 ; A61K31/444 ; A61K31/496 ; A61K31/437 ; A61K31/498 ; A61K31/541 ; A61K31/551 ; A61K31/5386 ; C12N9/99 ; A61K31/4709 ; A61K38/07 ; A61K31/501 ; A61K31/53 ; A61K9/127 ; A61P35/00 ; A61P37/00 ; A61P29/00 ; A61P13/12 ; A61K31/5377
摘要：
The present invention provides for a method for treating a disease condition associated with PI3-kinase α and/or mTOR in a subject. In another aspect, the invention provides for a method for treating a disease condition associated with PI3-kinase α and/or mTOR in a subject. In yet another aspect, a method of inhibiting phosphorylation of both Akt (S473) and Akt (T308) in a cell is set forth.
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