发明申请
- 专利标题： Processes and Recombinant Microorganisms for the Production of Cadaverine
- 专利标题（中）： 用于生产尸胺的方法和重组微生物
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申请号： US13516034申请日： 2010-12-15
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公开(公告)号： US20120295317A1公开(公告)日： 2012-11-22
- 发明人: Hartwig Schröder , Weol Kyu Jeong , Annegret Serwe , Oskar Zelder
- 申请人： Hartwig Schröder , Weol Kyu Jeong , Annegret Serwe , Oskar Zelder
- 申请人地址： DE Ludwigshafen
- 专利权人： BASF SE
- 当前专利权人： BASF SE
- 当前专利权人地址： DE Ludwigshafen
- 优先权： EP09179642.5 20091217
- 国际申请： PCT/EP2010/069802 WO 20101215
- 主分类号： C12P13/00
- IPC分类号： C12P13/00 ; C07C209/86 ; C12N1/21
摘要：
The present invention relates to the use of recombinant microorganisms comprising DNA molecules in a deregulated form which improve the production of cadaverine, as well as to recombinant DNA molecules and polypeptides used to produce the microorganism, said microorganism comprising an intracellular lysine decarboxylase activity and an enhanced lysine import activity or comprising an intracellular and an extracellular lysine decarboxylase activity or comprising an intracellular and extracellular lysine decarboxylase activity and an enhanced lysine import activity. The present invention also relates to a processes for the production of cadaverine using recombinant microorganisms.
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