发明申请
US20120295897A1 SPIRO-OXINDOLE COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS
有权
SPIRO-OXINDOLE化合物及其作为治疗剂的用途
- 专利标题: SPIRO-OXINDOLE COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS
- 专利标题(中): SPIRO-OXINDOLE化合物及其作为治疗剂的用途
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申请号: US13557833申请日: 2012-07-25
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公开(公告)号: US20120295897A1公开(公告)日: 2012-11-22
- 发明人: Mikhail Chafeev , Sultan Chowdhury , Lauren Fraser , Jianmin Fu , Jonathan Langille , Shifeng Liu , Jianyu Sun , Shaoyi Sun , Serguei Sviridov , Mark Wood , Alla Yurevna Zenova , Qi Jia , Jean-Jacques Cadieux , Simon J. Gauthier , Amy Frances Douglas , Tom Hsieh , Nagasree Chakka , Zoran Cikojevic
- 申请人: Mikhail Chafeev , Sultan Chowdhury , Lauren Fraser , Jianmin Fu , Jonathan Langille , Shifeng Liu , Jianyu Sun , Shaoyi Sun , Serguei Sviridov , Mark Wood , Alla Yurevna Zenova , Qi Jia , Jean-Jacques Cadieux , Simon J. Gauthier , Amy Frances Douglas , Tom Hsieh , Nagasree Chakka , Zoran Cikojevic
- 申请人地址: CA Burnaby
- 专利权人: Xenon Pharmaceuticals Inc.
- 当前专利权人: Xenon Pharmaceuticals Inc.
- 当前专利权人地址: CA Burnaby
- 主分类号: A61K31/407
- IPC分类号: A61K31/407 ; A61K31/429 ; C07D491/20 ; A61K31/4439 ; A61K31/422 ; C07D498/20 ; A61K31/424 ; A61K31/5383 ; C07D491/107 ; A61K31/475 ; C07D495/20 ; A61K31/4245 ; A61K31/4985 ; A61K31/4178 ; A61K31/4155 ; A61K31/5377 ; A61K31/427 ; A61K31/433 ; A61K31/497 ; A61K31/506 ; A61K31/454 ; A61K31/41 ; A61K31/496 ; A61P29/00 ; A61P25/24 ; A61P9/00 ; A61P11/00 ; A61P25/18 ; A61P3/06 ; A61P35/00 ; A61P17/04 ; C07D513/20
摘要:
This invention is directed to spiro-oxindole compounds, as stereoisomers, enantiomers, tautomers thereof or mixtures thereof; or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain.
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