Systems and methods are described for measuring orientation of sensors associated with a mobile device with respect to pedestrian motion of a user of the mobile device. An example technique described herein includes obtaining acceleration information associated with the mobile device, partitioning the acceleration information according to respective detected pedestrian steps of the user, identifying a forward motion direction of the user of the mobile device based on the acceleration information and the detected pedestrian steps, and computing a misalignment angle between the forward motion direction of the user of the mobile device and an orientation of the mobile device.