Invention Application
- Patent Title: MASS SPECTROMETRY METHOD
- Patent Title (中): 质谱法
-
Application No.: US13576124Application Date: 2011-03-28
-
Publication No.: US20120301968A1Publication Date: 2012-11-29
- Inventor: Jumpei Naito , Shuya Satoh , Manabu Komatsu , Hiroyuki Hashimoto
- Applicant: Jumpei Naito , Shuya Satoh , Manabu Komatsu , Hiroyuki Hashimoto
- Applicant Address: JP Tokyo
- Assignee: CANON KABUSHIKI KAISHA
- Current Assignee: CANON KABUSHIKI KAISHA
- Current Assignee Address: JP Tokyo
- Priority: JP2010-077842 20100330; JP2011-065780 20110324
- International Application: PCT/JP2011/058474 WO 20110328
- Main IPC: G01N27/62
- IPC: G01N27/62
Abstract:
The problem to be solved by the present invention is to provide a method for treating a polypeptide including a cysteine residue for enhancing the sensitivity of detection thereof in mass spectrometry using charged particles. A mass spectrometry method for a polypeptide including a cysteine residue is provided which includes treating the polypeptide including a cysteine residue with a cyanation agent, treating the cyanated polypeptide with a base, and then desorption ionizing the base-treated polypeptides using charged particles for mass spectrometry.
Public/Granted literature
- US09448241B2 Mass spectrometry method for a polypeptide including a cysteine residue Public/Granted day:2016-09-20
Information query
