发明申请
US20120302569A1 PHENYL-THIAZOLYL INHIBITORS OF PRO-MATRIX METALLOPROTEINASE ACTIVATION
审中-公开
PRO-MATRIX金属蛋白酶激活的苯基 - 噻唑啉酮抑制剂
- 专利标题： PHENYL-THIAZOLYL INHIBITORS OF PRO-MATRIX METALLOPROTEINASE ACTIVATION
- 专利标题（中）： PRO-MATRIX金属蛋白酶激活的苯基 - 噻唑啉酮抑制剂
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申请号： US13479395申请日： 2012-05-24
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公开(公告)号： US20120302569A1公开(公告)日： 2012-11-29
- 发明人: Paul Francis JACKSON , Kristi Anne Leonard , Joseph Kent Barbay , Aihua Wang , Brett Andrew Tounge , Yan Zhang , Umar S.M. Maharoof
- 申请人： Paul Francis JACKSON , Kristi Anne Leonard , Joseph Kent Barbay , Aihua Wang , Brett Andrew Tounge , Yan Zhang , Umar S.M. Maharoof
- 主分类号： A61K31/427
- IPC分类号： A61K31/427 ; A61K31/496 ; A61K31/4439 ; C07D417/14 ; A61K31/444 ; A61K31/454 ; C07D417/12 ; A61K31/5377 ; A61P35/00 ; A61P19/02 ; A61P29/00 ; A61P9/00 ; A61P1/04 ; A61P9/12 ; A61P11/00 ; A61P1/00 ; A61P1/02 ; A61P17/02 ; A61P1/16 ; A61P25/00 ; A61P11/06 ; A61P13/12 ; A61P25/06 ; A61P9/10 ; C07D417/10
摘要：
This invention relates to phenyl thiazole I and its therapeutic and prophylactic uses, wherein the variables Rz, Q, J, R1, R3, R5, R6, and R7 are defined in the specification. Disorders treated and/or prevented include rheumatoid arthritis.
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