Invention Application
US20120302573A1 METHODS OF INHIBITING PRO MATRIX METALLOPROTEINASE ACTIVATION
审中-公开
抑制PRO基质金属蛋白酶活化的方法
- Patent Title: METHODS OF INHIBITING PRO MATRIX METALLOPROTEINASE ACTIVATION
- Patent Title (中): 抑制PRO基质金属蛋白酶活化的方法
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Application No.: US13479421Application Date: 2012-05-24
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Publication No.: US20120302573A1Publication Date: 2012-11-29
- Inventor: Paul Francis JACKSON , Carl Manthey , Kenneth Rhodes , Robert Scannevin , Kristi Anne Leonard , Joseph Kent Barbay , Matthew Todd , Barry A. Springer
- Applicant: Paul Francis JACKSON , Carl Manthey , Kenneth Rhodes , Robert Scannevin , Kristi Anne Leonard , Joseph Kent Barbay , Matthew Todd , Barry A. Springer
- Main IPC: C12N9/99
- IPC: C12N9/99 ; A61K31/4439 ; A61K31/497 ; A61K31/437 ; A61K31/519 ; A61K31/444 ; A61K31/4985 ; A61P35/00 ; A61P19/02 ; A61P9/00 ; A61P1/04 ; A61P9/12 ; A61P11/00 ; A61P1/00 ; A61P1/02 ; A61P17/02 ; A61P25/06 ; A61K31/427
Abstract:
This invention relates to methods for preventing, treating or ameliorating an MMP9 and/or MMP13 mediated syndrome, disorder or disease comprising administering to a subject in need thereof an effective amount of a compound listed in the examples section of this specification, or a form, composition or medicament thereof. Disorders treated and/or prevented include rheumatoid arthritis.
Information query
