A high-pressure pressing arrangement includes two coaxial end closures; a high-pressure cylinder including two coaxial end openings, which are closable by the end closures; a frame for resisting outward axial movement of the end closures; a load basket for carrying articles to be treated, wherein the high-pressure cylinder and the frame are arranged transversally movable relative to each other between an operating position and a loading/unloading position; wherein, in the operating position, the end closures are positioned to cover the end apertures and in the loading/unloading position, at least one of the end closures is positioned to uncover at least one end aperture. Further, a first locking element is provided on an end closure and a second locking element is provided on an outward end surface of the load basket, so as to mate with the first element to prevent rotation of the load basket.