发明申请
- 专利标题: IMP-3 OLIGOPEPTIDES AND VACCINES INCLUDING THE SAME
- 专利标题(中): IMP-3寡核苷酸和疫苗,包括它们
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申请号: US13513120申请日: 2010-11-30
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公开(公告)号: US20120308590A1公开(公告)日: 2012-12-06
- 发明人: Yasuharu Nishimura , Michiko Harao , Yusuke Tomita , Yusuke Nakamura , Takuya Tsunoda
- 申请人: Yasuharu Nishimura , Michiko Harao , Yusuke Tomita , Yusuke Nakamura , Takuya Tsunoda
- 申请人地址: JP Kawasaki-shi
- 专利权人: OncoTherapy Science, Inc.
- 当前专利权人: OncoTherapy Science, Inc.
- 当前专利权人地址: JP Kawasaki-shi
- 国际申请: PCT/JP2010/006966 WO 20101130
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; C07H21/04 ; A61K31/7088 ; A61P35/00 ; A61K35/14 ; C07K7/06 ; C12N5/078
摘要:
Oligopeptides having cytotoxic T cell inducibility and suitable for use in the context of cancer immunotherapy, more particularly cancer vaccines are described herein. Notable examples include oligopeptides having the amino acid sequence of SEQ ID NO: 1, 3, 5 or 6, wherein 1, 2, or several amino acids are optionally substituted, deleted, inserted or added so long as they retain the cytotoxic T cell inducibility of the original oligopeptides. Pharmaceutical formulations or “drugs” related to such oligopeptides suitable for treating or preventing cancers or tumors, as well as the post-operative recurrence thereof, are also described.
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