发明申请
- 专利标题: TMEM22 PEPTIDES AND VACCINES INCLUDING THE SAME
- 专利标题(中): TMEM22肽和疫苗,包括它们
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申请号: US13515656申请日: 2010-12-13
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公开(公告)号: US20120308591A1公开(公告)日: 2012-12-06
- 发明人: Yusuke Nakamura , Takuya Tsunoda , Ryuji Ohsawa , Sachiko Yoshimura , Tomohisa Watanabe
- 申请人: Yusuke Nakamura , Takuya Tsunoda , Ryuji Ohsawa , Sachiko Yoshimura , Tomohisa Watanabe
- 申请人地址: JP Kawasaki-shi, Kanagawa
- 专利权人: Onco Therapy Science, Inc.
- 当前专利权人: Onco Therapy Science, Inc.
- 当前专利权人地址: JP Kawasaki-shi, Kanagawa
- 国际申请: PCT/JP2010/007228 WO 20101213
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; C12N15/12 ; C12N5/078 ; C12N1/21 ; C12N5/10 ; A61K31/7088 ; A61P35/00 ; C12N15/63 ; C07K7/06 ; C12N15/85
摘要:
Isolated peptides composed of the amino acid sequence of SEQ ID NO: 33 or fragments thereof that bind to HLA antigens and have cytotoxic T lymphocyte (CTL) inducibility and thus are suitable for use in the context of cancer immunotherapy, more particularly cancer vaccines are described herein. The present invention further provides peptides that include one, two, or several amino acid insertions, substitutions or additions to the aforementioned peptides or fragments, but yet retain the requisite cytotoxic T cell inducibility. Further provided are nucleic acids encoding any of these aforementioned peptides as well as pharmaceutical agents, substances and compositions including any of the aforementioned peptides or nucleic acids. The peptides, nucleic acids, pharmaceutical agents, substances and compositions of this invention find particular utility in the treatment of cancers and tumors.
公开/授权文献
- US08697631B2 TMEM22 peptides and vaccines including the same 公开/授权日:2014-04-15
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