发明申请
- 专利标题: PIPERAZINE COMPOUND HAVING A PGDS INHIBITORY EFFECT
- 专利标题(中): 具有PGDS抑制作用的哌嗪化合物
-
申请号: US13522605申请日: 2011-01-19
-
公开(公告)号: US20120309760A1公开(公告)日: 2012-12-06
- 发明人: Yoshihiro Urade , Makoto Kitade , Kazuhiko Shigeno , Keiko Yamane , Katsunao Tanaka
- 申请人: Yoshihiro Urade , Makoto Kitade , Kazuhiko Shigeno , Keiko Yamane , Katsunao Tanaka
- 申请人地址: JP Tokyo
- 专利权人: Taiho Pharmaceutical Co., Ltd.
- 当前专利权人: Taiho Pharmaceutical Co., Ltd.
- 当前专利权人地址: JP Tokyo
- 优先权: JP2010-012501 20100122
- 国际申请: PCT/JP2011/050840 WO 20110119
- 主分类号: A61K31/496
- IPC分类号: A61K31/496 ; A61P29/00 ; A61K31/5377 ; A61P37/08 ; C07D401/14 ; C07D413/14
摘要:
The present invention provides a piperazine compound represented by Formula (I) or a salt thereof, wherein X represents CH or an N atom; R1 represents C1-6 alkyl; R2 represents C1-6 alkyl that may have one or more substituents, C2-6 alkenyl that may have one or more substituents, —(C═O)—N(R3)(R4), or —(C═O)—OR5, R3 and R4 are the same or different, and each represents hydrogen or C1-6 alkyl that may have one or more substituents; or R3 and R4, taken together with a nitrogen atom to which R3 and R4 are attached, may form a saturated heterocyclic group; and R5 represents hydrogen or C1-6 alkyl that may have one or more substituents or aralkyl.
公开/授权文献
- US08765750B2 Piperazine compound having a PGDS inhibitory effect 公开/授权日:2014-07-01
信息查询
IPC分类: