发明申请
- 专利标题: PROCESS FOR THE PREPARATION OF CALCOBUTROL
- 专利标题(中): 制备加工液的方法
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申请号: US13508198申请日: 2010-11-02
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公开(公告)号: US20120309962A1公开(公告)日: 2012-12-06
- 发明人: Johannes Platzek , Wilhelm Trentmann
- 申请人: Johannes Platzek , Wilhelm Trentmann
- 申请人地址: DE Monheim
- 专利权人: Bayer Intellectual Property GmbH
- 当前专利权人: Bayer Intellectual Property GmbH
- 当前专利权人地址: DE Monheim
- 优先权: DE102009053171.8 20091104
- 国际申请: PCT/EP2010/066655 WO 20101102
- 主分类号: C07D257/02
- IPC分类号: C07D257/02
摘要:
The invention concerns a process for the preparation of the calcium complex of 0-(2,3-Dihydroxy-1-(hydroxymethyl)propyl)-1,4,7,10-tetraazacyclodecane-4,7-triacetic acid, also known as Calcobutrol, starting from the pure gadolinium complex (Gadobutrol). The invention furthermore concerns Calcobutrol with a hitherto unknown level of purity.
公开/授权文献
- US09447053B2 Process for the preparation of calcobutrol 公开/授权日:2016-09-20
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