发明申请
- 专利标题: EXTENDED RELEASE PREPARATION
- 专利标题(中): 扩展发布准备
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申请号: US13578323申请日: 2011-02-10
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公开(公告)号: US20120316177A1公开(公告)日: 2012-12-13
- 发明人: Noriyuki Hirasawa , Nobuyoshi Kamikido , Akihiko Tasaki , Shusei Ito
- 申请人: Noriyuki Hirasawa , Nobuyoshi Kamikido , Akihiko Tasaki , Shusei Ito
- 申请人地址: JP Chiyoda-ku, Tokyo JP Toshima-ku, Tokyo
- 专利权人: NISSAN CHEMICAL INDUSTRIES, LTD.,TAISHO PHARMACEUTICAL CO., LTD
- 当前专利权人: NISSAN CHEMICAL INDUSTRIES, LTD.,TAISHO PHARMACEUTICAL CO., LTD
- 当前专利权人地址: JP Chiyoda-ku, Tokyo JP Toshima-ku, Tokyo
- 优先权: JP2010-028984 20100212
- 国际申请: PCT/JP2011/052909 WO 20110210
- 主分类号: A61K31/501
- IPC分类号: A61K31/501 ; A61P11/06
摘要:
Disclosed is a sustained release preparation which releases a poorly soluble medicinal agent in a pH-independent manner. Also disclosed is a sustained release preparation which is capable of controlling the Cmax of a medicinal agent to an adequate amount and is thus capable of maintaining the level of the medicinal agent in the blood to a level at which medicinal effects can be expected for a long period of time. Specifically disclosed is a sustained release preparation which is characterized by containing a pharmaceutically acceptable salt of 4-bromo-6-[3-(4-chlorophenyl)propoxy]-5-(3-pyridylmethylamino)-3(2H)-pyridazinone, and hypromellose. An organic acid is blended in the sustained release preparation in an amount of less than 1% by mass.
公开/授权文献
- US08912192B2 Extended release preparation 公开/授权日:2014-12-16
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