发明申请
US20120321658A1 IMMUNOGENIC COMPOSITION COMPRISING S. PNEUMONIAE POLYSACCHARIDES CONJUGATED TO CARRIER PROTEINS
审中-公开
包含与载体蛋白结合的S. PNEUMONIAE多糖的免疫组合物
- 专利标题： IMMUNOGENIC COMPOSITION COMPRISING S. PNEUMONIAE POLYSACCHARIDES CONJUGATED TO CARRIER PROTEINS
- 专利标题（中）： 包含与载体蛋白结合的S. PNEUMONIAE多糖的免疫组合物
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申请号： US13581686申请日： 2010-08-17
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公开(公告)号： US20120321658A1公开(公告)日： 2012-12-20
- 发明人: Ralph Leon Biemans , Pierre Duvivier , Ollivier Francis Nicolas Gavard , Jan Poolman
- 申请人： Ralph Leon Biemans , Pierre Duvivier , Ollivier Francis Nicolas Gavard , Jan Poolman
- 优先权： GB10039247.6 20100309
- 国际申请： PCT/EP2010/061963 WO 20100817
- 主分类号： C07K17/10
- IPC分类号： C07K17/10 ; A61P37/04 ; A61K39/385
摘要：
The present invention relates to an immunogenic composition comprising at least 2 different S. pneumoniae capsular saccharides, wherein one or more is/are selected from a first group consisting of serotypes 1, 3, 19A and 19F which is/are linked to a protein carrier(s) either directly or indirectly through a chemistry other than reductive amination, and one or more different saccharides is/are selected from a second group consisting of serotypes 4, 5, 6A, 6B, 7F, 9V, 14, 18C and 23F which is/are linked to a protein carrier(s) by reductive amination. Uses of such compositions are also disclosed.
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