Invention Application
- Patent Title: Modulators of ATP-Binding Cassette Transporters
- Patent Title (中): ATP结合盒转运蛋白的调节剂
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Application No.: US13595225Application Date: 2012-08-27
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Publication No.: US20120322798A1Publication Date: 2012-12-20
- Inventor: Sara S. Hadida Ruah , Matthew Hamilton , Mark Miller , Peter D.J. Grootenhuis , Brian Bear , Jason McCartney , Jinglan Zhou
- Applicant: Sara S. Hadida Ruah , Matthew Hamilton , Mark Miller , Peter D.J. Grootenhuis , Brian Bear , Jason McCartney , Jinglan Zhou
- Applicant Address: US MA Cambridge
- Assignee: VERTEX PHARMACEUTICALS INCORPORATED
- Current Assignee: VERTEX PHARMACEUTICALS INCORPORATED
- Current Assignee Address: US MA Cambridge
- Main IPC: A61K31/4439
- IPC: A61K31/4439 ; A61K31/4545 ; A61K31/5377 ; A61K31/444 ; A61K31/496 ; A61K31/501 ; A61K31/506 ; A61K31/497 ; A61K31/4709 ; A61P3/06 ; A61P3/10 ; A61P17/00 ; A61P5/00 ; A61P25/00 ; A61P25/28 ; A61P25/16 ; A61K31/443
Abstract:
Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTC”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
Public/Granted literature
- US08461156B2 Modulators of ATP-binding cassette transporters Public/Granted day:2013-06-11
Information query
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