A tire inflation system comprising a tire inflation apparatus having an inflation head, a pressurized gas source, and a controller, with the inflation head being positioned at a tire and wheel assembly inflation location at which a tire and wheel assembly is received to inflate the tire and wheel assembly. The tire and wheel assembly includes a tire pressure monitoring (TPM) valve stem that detects and transmits inflation pressure data of the tire and wheel assembly. The inflation head defines a tire inflation cavity that seals with the tire of the tire and wheel assembly when engaged with the inflation head. Pressurized gas is delivered from the pressurized gas source through an outlet in the tire inflation cavity for inflation of the tire and wheel assembly. The controller receives inflation pressure data from the TPM valve stem and controls operation of the tire inflation apparatus in response thereto.