Invention Application
US20120328588A1 COMPOUND PREPARATION AND ITS USES FOR PREVENTION AND TREATMENT OF HEARING IMPAIRMENT
审中-公开
化合物的制备及其用于预防和治疗听觉障碍的用途
- Patent Title: COMPOUND PREPARATION AND ITS USES FOR PREVENTION AND TREATMENT OF HEARING IMPAIRMENT
- Patent Title (中): 化合物的制备及其用于预防和治疗听觉障碍的用途
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Application No.: US13582755Application Date: 2011-05-08
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Publication No.: US20120328588A1Publication Date: 2012-12-27
- Inventor: Shen Gao , Jing Gao , Quangang Zhu , Xiying Wang , Xueying Ding , Wei Zhang , Xiaoyu Wang , Min Zhang , Xin Wu , Lihua Ye
- Applicant: Shen Gao , Jing Gao , Quangang Zhu , Xiying Wang , Xueying Ding , Wei Zhang , Xiaoyu Wang , Min Zhang , Xin Wu , Lihua Ye
- Applicant Address: CN Shanghai
- Assignee: The Second Military Medical University of Chinese PLA
- Current Assignee: The Second Military Medical University of Chinese PLA
- Current Assignee Address: CN Shanghai
- Priority: CN201010180892.X 20100524
- International Application: PCT/CN2011/073796 WO 20110508
- Main IPC: A61K31/4422
- IPC: A61K31/4422 ; A61P27/16
Abstract:
A compound preparation contains alpha-lipoic acid and nimodipine at a ratio from 5:1 to 40:1. The above-mentioned compound preparation can be used for the prevention and treatment of noise-induced hearing impairment. This compound preparation not only increases the efficacy but decreases the dosage of nimodipine, reduces the side effects and improves the patient compliance.
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