A system and method of determining calibration data at non-calibrated location points is disclosed. A mobile station may be geo-located at most locations, if not all locations, within communication range of one or more serving and/or neighboring base stations of a mobile network. Calibration data may be collected and stored in memory via a data collection procedure. Known calibration data for locations proximate to the mobile station may be necessary when attempting to geo-locate the mobile station. A geographical region may be calibrated via a standard calibration data collection procedure, however, various obstacles, such as, buildings, mountains, ponds etc. may inevitably create deficiencies in the calibration data for one or more areas of the region. Certain techniques may be applied to estimate the calibration data of areas that have not been properly calibrated.