A fluid delivery device includes a cartridge and a syringe. The cartridge includes a housing and a stopper positioned within a fluid chamber defined by the housing. The syringe includes a needle, and an outer body and an inner core which cooperate to receive at least a portion of the housing. When the fluid delivery device is in a first configuration, at least a portion of the cartridge is positioned within the syringe and the stopper is connected to the inner core. In a second configuration, a lumen defined by the needle is in fluid communication with the fluid chamber. The inner core and stopper are movable distally relative to the outer body and needle as the fluid delivery device is transitioned from the first to the second configuration. In a third configuration, the cartridge and syringe cooperate to disable the fluid delivery device.