A flow battery stack includes an inlet manifold, an outlet manifold and a plurality of flow battery cells. The inlet and outlet manifolds each have first and second passages. The first and second passages in at least one of the inlet and outlet manifolds are tortuous. Each flow battery cell includes a separator arranged between a first electrode layer and a second electrode layer. The flow battery cells are axially connected between the inlet manifold and the outlet manifold such that a first solution having a first reversible redox couple reactant is directed from the inlet first passage through the flow battery cells, wetting the first electrode layers, to the outlet first passage.