发明申请
- 专利标题: NOVEL GLUCOKINASE ACTIVATORS AND METHODS OF USING SAME
- 专利标题(中): 新型GLUCOKINASE激活剂及其使用方法
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申请号: US13640767申请日: 2011-04-14
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公开(公告)号: US20130029939A1公开(公告)日: 2013-01-31
- 发明人: Wei Meng , Peter T.W. Cheng
- 申请人: Wei Meng , Peter T.W. Cheng
- 专利权人: Bristol-Myers Squibb Company
- 当前专利权人: Bristol-Myers Squibb Company
- 国际申请: PCT/US11/32386 WO 20110414
- 主分类号: A61K31/675
- IPC分类号: A61K31/675 ; A61P3/10 ; A61P3/04 ; A61P9/12 ; A61P25/00 ; A61P17/02 ; A61P9/10 ; A61P3/06 ; A61P31/00 ; A61P35/00 ; A61P25/28 ; A61P1/18 ; A61P19/08 ; A61P27/06 ; C07F9/6558
摘要:
Compounds are provided which are activators of the enzyme glucokinase and thus are useful in treating diabetes and related diseases, which compounds have the structure wherein R1, R2, R3, R4, R5, R6, Y and X are as defined herein or a pharmaceutically acceptable salt thereof. A method for treating diabetes and related disease employing the above compounds is also provided.
公开/授权文献
- US08592396B2 Glucokinase activators and methods of using same 公开/授权日:2013-11-26
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