A urinal screen assembly is provided. The urinal screen assembly includes a base having opposing major surfaces, a plurality of apertures extending therebetween and a rim. The base is configured to seat in a contoured orientation against contours on a surface of a urinal bowl. The base includes one or more deodorizing and cleaning agents. A retention structure extends from one of the major surfaces of the base. A block is positioned within the retention structure. The block includes one or more deodorizing and cleaning agents configured to deodorize and clean the urinal bowl. The deodorizing and cleaning agents in the base and the deodorizing and cleaning agents in the block are configured to combine to form a deodorizing and cleaning zone that extends radially beyond the edges of the block.