An autostereoscopic display device having touch sensing mechanism includes a display panel for illustrating images, a touch sensing panel for detecting touch events, a 2D/3D switching panel disposed between the display panel and the touch sensing panel, and a control unit. The 2D/3D switching panel has a substrate, a first electrode disposed on the substrate, a counter substrate, and a second electrode disposed on the counter substrate. The control unit is employed to provide a first control signal and a second control signal furnished to the first electrode and the second electrode respectively. The first control signal is switched between a first high voltage and a first low voltage in a gradual-shift manner. The second control signal is switched between a second high voltage and a second low voltage in a gradual-shift or rapid-shift manner.