发明申请
- 专利标题: REPROGRAMMATION OF EUKARYOTIC CELLS WITH ENGINEERED MICROVESICLES
- 专利标题(中): 用工程微量元素代替重组细胞
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申请号: US13505934申请日: 2010-11-10
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公开(公告)号: US20130034900A1公开(公告)日: 2013-02-07
- 发明人: Philippe Mangeot , Vincent Lotteau , Marc Peschanski , Mathilde Girard
- 申请人: Philippe Mangeot , Vincent Lotteau , Marc Peschanski , Mathilde Girard
- 申请人地址: FR Paris
- 专利权人: INSERM (Institut National de la Sante et de la Recherche Midicale)
- 当前专利权人: INSERM (Institut National de la Sante et de la Recherche Midicale)
- 当前专利权人地址: FR Paris
- 优先权: EP09306092.9 20091113
- 国际申请: PCT/EP10/67225 WO 20101110
- 主分类号: C12N5/07
- IPC分类号: C12N5/07 ; C12N5/073
摘要:
The present invention relates to a non-genetic, detergent-free, bacteria-free method for reprogramming a eukaryotic cell, in particular for obtaining induced pluripotent stem cells (iPS), by using engineered microvesicles carrying at least one reprogramming transcription factor, wherein said engineered microvesicles are virus-free.
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