发明申请
- 专利标题: Thalidomide Analogs
- 专利标题(中): 沙利度胺类似物
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申请号: US13648625申请日: 2012-10-10
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公开(公告)号: US20130035363A1公开(公告)日: 2013-02-07
- 发明人: Nigel H. Greig , Harold Holloway , Arnold Brossi , Xiaoxiang Zhu , Tony Giordano , Qian-sheng Yu , William D. Figg
- 申请人: Nigel H. Greig , Harold Holloway , Arnold Brossi , Xiaoxiang Zhu , Tony Giordano , Qian-sheng Yu , William D. Figg
- 申请人地址: US DC Washington US OH Cincinnati
- 专利权人: The United States of America as represented by the Department of Health & Human Services,P2D INC.
- 当前专利权人: The United States of America as represented by the Department of Health & Human Services,P2D INC.
- 当前专利权人地址: US DC Washington US OH Cincinnati
- 主分类号: A61K31/4035
- IPC分类号: A61K31/4035 ; A61P3/04 ; A61P19/02 ; A61P31/04 ; A61P1/00 ; A61P35/00 ; A61P25/00 ; A61P25/28 ; A61P25/16 ; A61P7/04 ; A61P27/02 ; A61P29/00 ; A61P1/04
摘要:
Thalidomide analogs that modulate tumor necrosis factor alpha (TNFα) activity and angiogenesis are disclosed. In particularly disclosed embodiments, the thalidomide analogs are isosteric sulfur-containing analogs. Also disclosed are methods of treating a subject with the analogs.
公开/授权文献
- US08853253B2 Thalidomide analogs 公开/授权日:2014-10-07
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