A smart HVAC system adapted for selectively regulating fluid flow into a space generally includes an HVAC system including at least one active vent, a preferably variable blower fluidly coupled thereto, and at least one sensor associated with each vent, wherein the sensor is operable to cause the associated vent to shift between opened and closed conditions, and/or preferably the blower output to change, when an occupant is autonomously detected within at least a portion of the space.