发明申请
US20130040992A1 Substituted 2, 6-Diamino-3, 5-Dicyano-4-Aryl-Pyridines And Their Use As Adenosine-Receptor-Selective Ligands
审中-公开
取代的2,6-二氨基-3,5-二氰基-4-芳基吡啶及其作为腺苷受体选择性配体
- 专利标题： Substituted 2, 6-Diamino-3, 5-Dicyano-4-Aryl-Pyridines And Their Use As Adenosine-Receptor-Selective Ligands
- 专利标题（中）： 取代的2,6-二氨基-3,5-二氰基-4-芳基吡啶及其作为腺苷受体选择性配体
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申请号： US13584722申请日： 2012-08-13
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公开(公告)号： US20130040992A1公开(公告)日： 2013-02-14
- 发明人: Ulrich Rosentreter , Thomas Krämer , Andrea Vaupel , Walter Hübsch , Nicole Diedrichs , Thomas Krahn , Klaus Dembowsky , Johannes-Peter Stasch
- 申请人： Ulrich Rosentreter , Thomas Krämer , Andrea Vaupel , Walter Hübsch , Nicole Diedrichs , Thomas Krahn , Klaus Dembowsky , Johannes-Peter Stasch
- 申请人地址： DE Monheim
- 专利权人： BAYER INTELLECTUAL PROPERTY GMBH
- 当前专利权人： BAYER INTELLECTUAL PROPERTY GMBH
- 当前专利权人地址： DE Monheim
- 优先权： DE10110747.1 20010307
- 主分类号： A61K31/444
- IPC分类号： A61K31/444 ; A61K31/4418 ; C07D401/12 ; A61K31/4439 ; C07D409/12 ; A61K31/4436 ; A61K31/443 ; C07D405/14 ; C07D417/14 ; A61P9/00 ; A61P9/12 ; A61P9/06 ; A61P9/10 ; A61P25/00 ; C07D213/85
摘要：
The present invention relates to substituted 2,6-diamino-3,5-dicyano-4-arylpyridines of the formula (I) wherein the definitions of substituent groups R1-R7 are as provided in the specification and claims, to a pharmaceutical composition containing such a compound, to a process for preparation of such materials, and to their use as medicaments for the treatment of cardiovascular disorders and diabetes.
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