Size reduction is achieved while also achieving both high sensitivity and high pixel density. Provided is an image acquisition device including an image acquisition element that acquires an image of a sample, a closed container that accommodates and seals the image acquisition element therein, a camera body that accommodates the closed container, and a displacement member that moves the image acquisition element relative to the camera body in a direction perpendicular to an optical axis of the image acquisition element. At least a portion of the displacement member is disposed outside the closed container.