发明申请
US20130054171A1 System and Method for Correcting Primer Extension Errors in Nucleic Acid Sequence Data 有权
用于校正核酸序列数据中引物延伸错误的系统和方法

  • 专利标题: System and Method for Correcting Primer Extension Errors in Nucleic Acid Sequence Data
  • 专利标题(中): 用于校正核酸序列数据中引物延伸错误的系统和方法
  • 申请号: US13608841
    申请日: 2012-09-10
  • 公开(公告)号: US20130054171A1
    公开(公告)日: 2013-02-28
  • 发明人: Yi-Ju ChenKeith McDadeJohn Simpson
  • 申请人: Yi-Ju ChenKeith McDadeJohn Simpson
  • 主分类号: G06F19/18
  • IPC分类号: G06F19/18
System and Method for Correcting Primer Extension Errors in Nucleic Acid Sequence Data
摘要:
An embodiment of method for correcting an error associated with phasic synchrony of sequence data generated from a population of substantially identical copies of a template molecule is described that comprises (a) detecting a signal generated in response to an incorporation of one or more nucleotides in a sequencing reaction; (b) generating a value for the signal; and (c) correcting the value for the phasic synchrony error using a first parameter and a second carry forward parameter.
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