A transmission guide comprises a synthetic resin shoe and a more rigid synthetic resin base, integrally molded by two-member molding. The base is formed with a pair of spaced, opposed, side walls extending in the direction of elongation of the base along opposite edges of a shoe-supporting surface of the base. These side walls engage respective side edges of the shoe, and extend past the front surface of the shoe so that they can restrict lateral movement of a transmission chain sliding along the front surface of the shoe. Indentations in the side walls receive protrusions formed on the edges of the shoe. Edges of the openings of the indentations are chamfered or convexly curved to avoid interference with the movement of the chain along the guide.