A clamp for securing a surgical instrument or tubing to surgical drapes is provided. The clamp may be attached to surgical drapes and include a retaining member for engaging the cable of a surgical instrument or tubing. The clamp secures the surgical instrument or tubing to the surgical drapes so as to prevent the surgical instrument or tubing from falling outside the sterile field while allowing for convenient repositioning of the surgical instrument when desired. The clamp may also include an attachment member to minimize the risk of tearing of the surgical drapes when the clamp is attached thereto. Additionally, the clamp may include a gripping member that allows the user to operate the clamp while using surgical gloves.