Invention Application
US20130065826A1 Injectable solution at pH 7 Comprising at least one basal insulin whose PI is between 5.8 and 8.5 有权
pH7的可注射溶液包括至少一种PI在5.8和8.5之间的基础胰岛素

  • Patent Title: Injectable solution at pH 7 Comprising at least one basal insulin whose PI is between 5.8 and 8.5
  • Patent Title (中): pH7的可注射溶液包括至少一种PI在5.8和8.5之间的基础胰岛素
  • Application No.: US13571026
    Application Date: 2012-08-09
  • Publication No.: US20130065826A1
    Publication Date: 2013-03-14
  • Inventor: Olivier SOULAGérard SOULAJeff TONNAR
  • Applicant: Olivier SOULAGérard SOULAJeff TONNAR
  • Applicant Address: FR Lyon
  • Assignee: ADOCIA
  • Current Assignee: ADOCIA
  • Current Assignee Address: FR Lyon
  • Priority: FR11/57291 20110810; FR11/62445 20111223
  • Main IPC: A61K38/28
  • IPC: A61K38/28 A61P3/10
Injectable solution at pH 7 Comprising at least one basal insulin whose PI is between 5.8 and 8.5
Abstract:
A composition in the form of an injectable aqueous solution, the pH of which is between 6.0 and 8.0, includes at least a basal insulin, the isoelectric point pI of which is between 5.8 and 8.5; and a dextran substituted by radicals carrying carboxylate charges and hydrophobic radicals. Single-dose formulations at a pH of between 7 and 7.8 includes a basal insulin whose isoelectric point is between 5.8 and 8.5 and a prandial insulin.
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