发明申请
US20130079243A1 Fibronectin Type III Repeat Based Protein Scaffolds with Alternative Binding Surfaces
审中-公开
具有替代结合表面的纤连蛋白III型重复基于蛋白质支架
- 专利标题: Fibronectin Type III Repeat Based Protein Scaffolds with Alternative Binding Surfaces
- 专利标题(中): 具有替代结合表面的纤连蛋白III型重复基于蛋白质支架
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申请号: US13628393申请日: 2012-09-27
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公开(公告)号: US20130079243A1公开(公告)日: 2013-03-28
- 发明人: Michael Diem , Steven Jacobs
- 申请人: Michael Diem , Steven Jacobs
- 申请人地址: US PA Horsham
- 专利权人: JANSSEN BIOTECH, INC.
- 当前专利权人: JANSSEN BIOTECH, INC.
- 当前专利权人地址: US PA Horsham
- 主分类号: C40B40/10
- IPC分类号: C40B40/10 ; C40B30/04 ; C40B50/06
摘要:
Protein scaffolds and scaffold libraries based on a fibronectin type III (FN3) repeat with an alternative binding surface design, isolated nucleic acids encoding the protein scaffolds, vectors, host cells, and methods of making thereof are useful in the generation of therapeutic molecules and treatment and diagnosis of diseases and disorders.
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